Domingo, 22 Octubre, 2017

Strawberries may help fight breast cancer

Study on mice demonstrates the action of strawberries against breast cancer Researchers used strawberry extract to perform their experiments. Credit M. Battino et
Danilo Martir | 21 Abril, 2017, 02:59

Plataforma SINC reports that a study which was done by researchers in Europe and Latin America has demonstrated that strawberry extract can inhibit the spread of breast cancer cells grown in a lab.

Despite the positive results, the researchers said the information from this study and other studies using animal models should not be extrapolated to humans.

This decreased cell viability (dependent on dosage and time), blocked the cycle leading to cell division and inhibited migration, researchers said. Previous studies found that eating 500 grams of strawberries daily (between 10 and 15 strawberries), offered antioxidant benefits and reduced cholesterol levels.

This suggests that strawberry extracts may serve as an effective preventive and curative food intervention for breast cancer in people. At the same time, the extract stimulated expression of the gene Htatip2, which is thought to suppress metastasis to the lymph nodes of breast cancer patients.

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Scientists at the Salk Institute for Biological Studies studied mice with Alzheimer's symptoms and found that when they were given fisetin, a type of flavonol that's found in strawberries, they began producing anti-inflammatory molecules, and both memory loss and learning impairments were prevented.

The in vivo model used female laboratory mice, which at one month of age were divided into two groups: one was given a standard diet, while the other group was given an enriched diet, 15 percent of which was strawberry extract. After another month, all the mice were injected with A17 breast cancer cells.

The tumours were monitored twice weekly by palpation.

Recent studies have shown that strawberries might be the next miracle fruit to cut down breast-cancer risk as the extracts are found to prevent growth of carcinogenic cells and reduce tumour size.

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After five weeks, the tumours were extracted and analysed to evaluate their weight and volume.

"We also saw a significant reduction in the weight and volume of the tumour", Battino said.

"The majority of diseases, including cancer, are complex, and involve complex interactions between cellular and molecular systems that determine the development of the disease", Dr Battino continued.

Despite the positive results of the study, in which researchers from the University of the Americas (Ecuador) and the International Iberoamerican University (Mexico) also participated, the researcher emphasises that the information from this and other studies using animal models cannot be extrapolated to humans.

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The researchers also said that the concentration of phenolic compounds can vary greatly between varieties of strawberry.

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